Key session presented at the 40th Annual Meeting of European Society of Human Reproduction and Embryology, 7-10 July 2024, Amsterdam, The Netherlands

Key session presented at the 40th Annual Meeting of European Society of Human Reproduction and Embryology, 7-10 July 2024, Amsterdam, The Netherlands

New research confirmed that offspring of parents diagnosed with IBD before childbirth face a substantial risk of developing IBD themselves. Children of mothers with pre-birth IBD had an adjusted HR of 6.27 for IBD, compared to 3.88 for those whose mothers were diagnosed after childbirth. Paternal IBD showed similar patterns, with pre-birth IBD diagnoses having an HR of 5.26 versus 3.73 for post-birth diagnoses.

In 654 snoring patients, those with higher triglyceride-glucose index quartiles had a markedly increased risk of NAFLD, with the highest quartile showing an odds ratio of 5.12. The TyG index showed a strong dose-response relationship with NAFLD risk. Combining the TyG index with neck circumference and the Epworth Sleepiness Scale score provides a reliable screening method for NAFLD in this patient group (AUC: 0.746).

In over 17,000 NHANES survey participants, researchers found that each 10-point increase in LE8 score was associated with a 9% decrease in the odds of RA (OR, 0.91). Notably, higher LE8 scores reflecting better sleep health, lower nicotine exposure, optimal BMI & controlled BP were significant factors in this protective effect, with the association being particularly strong among younger individuals and women.

A global study across 25 countries found that activity limitations are most prevalent among women & in low- & middle-income regions. Common challenges include bending, seeing close & walking that worsen with age. The use of assistive devices like gait, visual & hearing aids was lowest in these regions, despite higher need. Walking limitations were strongly tied to higher mortality (aHR 1.32) & adverse clinical events...