The WARRIOR trial found no significant reduction in MACE with IMT in women with INOCA, impacted by high contamination and non-adherence. STRIDE showed Semaglutide significantly improved walking distance, quality of life, and reduced disease progression by 54% in PAD patients with T2D. API-CAT demonstrated reduced-dose apixaban was non-inferior to full-dose in preventing recurrent VTE in cancer patients.

The 2024 PAD guidelines shift focus from procedures to multidisciplinary care and risk modification. DPI (rivaroxaban + aspirin) now has a Class 1A recommendation over DAPT post-procedure. Lp(a) testing is gaining relevance despite no approved therapy. Early detection using ABI, team-based care, and tackling barriers to DPI access are key to improving outcomes.

Asthma significantly elevated the risk of cardiovascular diseases (CVD) & cardiovascular mortality (CVM), a meta-analysis found. Data from 29 studies with over 11 million participants revealed a 35% higher risk of coronary heart disease, a 48% greater risk of angina pectoris, a 33% higher risk of myocardial infarction & a 53% higher risk of heart failure. Asthma also raised overall CVD (RR 1.30) and CVM (RR 1.26).

Women with rheumatoid arthritis (RA) face a higher risk of developing premenstrual dysphoric disorder (PMDD) compared to healthy controls. The prevalence of PMDD was 24% in women with RA, nearly four times higher than the 6% observed in healthy women. Functional impairment due to PMDD was also more common in the RA group (28.4% vs. 7.5%), underscoring the greater burden of PMDD in this population.

A global meta-analysis revealed soaring myopia prevalence in children using digital devices. 28.8% of children using computer and video games, 35.4% watching TV, and 31.4% using smartphones were affected by myopia. Screen exposure was flagged as a rising threat to children’s eye health, reinforcing the need for early screening and reduced device time to prevent long-term vision issues.

High-intensity occupational physical activity (OPA) was linked to a greater risk of obstructive sleep apnea (OSA), especially in older adults (> 60 years) (OR 1.32), those with a BMI above 25 (OR 1.96), and hypertensive patients (OR 3.72). A study revealed that intense OPA increased the risk of OSA by 73% (OR 1.73), whereas no such association was observed between leisure-time physical activity (LTPA) and OSA risk.