Have you observed a higher incidence of cardiovascular disease in patients with elevated estimated glucose disposal rate in CKM syndrome?
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A large-scale study uncovered a U-shaped link between estimated glucose disposal rate (eGDR) and cardiovascular disease (CVD) in Cardiovascular-Kidney-Metabolic (CKM) syndrome stages 0-3. An eGDR below 11.82 mg/kg/min was associated with a 12% lower CVD risk per unit increase, while higher values were tied to a 19% higher risk per unit increase, highlighting the need for a balanced glucose state in CKM management.
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